| 9/15/18 |
| Pocono Mountain West 56, William Allen 28 |
| 9/14/18 |
| Bangor 28, Southern Lehigh 20 |
| Bethlehem Catholic 24, Parkland 16 |
| Bethlehem Freedom 49, Nazareth Area 28 |
| Easton Area 28, Bethlehem Liberty 21 |
| Emmaus 56, Pleasant Valley 0 |
| Lehighton 26, Marian Catholic 6 |
| Mahanoy Area 25, Nativity BVM 24 |
| Midd-West 30, Shenandoah Valley 0 |
| North Schuylkill 54, Schuylkill Haven 0 |
| Northampton 50, East Stroudsburg North 0 |
| Northern Lehigh 14, Pen Argyl 3 |
| Northwestern Lehigh 31, Wilson Area 14 |
| Notre Dame 35, Palmerton Area 20 |
| Palisades 54, Catasauqua 22 |
| Pocono Mountain East 29, Louis E. Dieruff 18 |
| Saucon Valley 41, Salisbury Township 27 |
| Stroudsburg 40, East Stroudsburg South 20 |
| Tamaqua Area 71, Panther Valley 0 |
| Tri-Valley 20, Pine Grove Area 15 |
| Whitehall 75, Allentown Central Catholic 35 |
| Wyomissing Area 28, Blue Mountain 16 |
