| 10/13/18 |
| Sayre 46, Cowanesque Valley 13 |
| 10/12/18 |
| Athens 24, Midd-West 19 |
| Bloomsburg 35, Hughesville 20 |
| Canton Area 26, Wellsboro 16 |
| Central Columbia 49, Warrior Run 0 |
| Danville 47, Shamokin 14 |
| Jersey Shore 25, Lewisburg 17 |
| Line Mountain 22, Pine Grove Area 20 |
| Loyalsock Township 30, Milton Area 7 |
| Montoursville 35, Mifflinburg 21 |
| Mount Carmel Area 55, South Williamsport 13 |
| Muncy 50, Columbia-Montour Vo-Tech 6 |
| North Penn/Mansfield 38, Towanda 6 |
| Northwest Area 35, Wyalusing Area 8 |
| Southern Columbia 69, Shikellamy 7 |
| Troy Area 31, Montgomery 14 |
