| 9/8/18 |
| Academy Park 39, Great Valley 22 |
| Archbishop Ryan 41, Interboro 14 |
| Avon Grove 24, Unionville 22 |
| Bristol 28, Pennington School (NJ) 26 |
| Cardinal O’Hara 21, Sun Valley 7 |
| Downingtown West 35, Neshaminy 14 |
| Garnet Valley 14, Haverford High 7 |
| Glen Mills 24, West Chester Henderson 9 |
| Harry S. Truman 49, William Tennent 14 |
| Lansdale Catholic 35, Wissahickon 14 |
| Marple-Newtown 21, Lower Merion 20 |
| Norristown 26, Plymouth-Whitemarsh 14 |
| North Penn 33, Pennsbury 7 |
| Perkiomen Valley 18, Pennridge 12 |
| Pope John Paul II 21, Chichester 20 |
| Radnor 42, Harriton 8 |
| Springfield-Delco 17, Ridley 16 |
| Springfield-Montco 43, Valley Forge Military Academy 14 |
| Strath Haven 35, Penncrest 0 |
| Upper Darby 41, Conestoga 14 |
| Upper Merion 14, Methacton 0 |
| Upper Moreland 48, Upper Perkiomen 33 |
| West Chester East 31, West Chester Rustin 21 |
| 9/7/18 |
| Abington 27, Cheltenham 0 |
| Academy of the New Church 38, New Hope Solebury 37 |
| Central Bucks East 41, Bensalem 12 |
| Coatesville 35, Cumberland Valley 19 |
| Council Rock South 27, Central Bucks South 17 |
| Downingtown East 42, Roman Catholic 7 |
| Hatboro-Horsham 8, Souderton Area 7 |
| Oxford Area 28, Owen J. Roberts 9 |
| Pottsgrove 34, Boyertown 8 |
| Quakertown Community 21, Central Bucks West 19 |
| 9/6/18 |
| Phoenixville 21, Kennett 14 |
