| 10/13/18 |
| Pocono Mountain West 53, Pleasant Valley 6 |
| Wilson Area 28, Palmerton Area 27 |
| 10/12/18 |
| Bangor 45, Salisbury Township 10 |
| Bethlehem Catholic 28, Easton Area 7 |
| Bethlehem Freedom 32, Emmaus 31 |
| Bethlehem Liberty 32, Allentown Central Catholic 14 |
| East Stroudsburg South 53, Louis E. Dieruff 18 |
| Jim Thorpe Area 30, Pottsville Area 16 |
| Mahanoy Area 35, Panther Valley 0 |
| Marian Catholic 39, Shenandoah Valley 7 |
| Nativity BVM 28, Bucktail 20 |
| Nazareth Area 28, Whitehall 7 |
| North Schuylkill 51, Blue Mountain 21 |
| Northampton 62, William Allen 7 |
| Northwestern Lehigh 49, Saucon Valley 28 |
| Notre Dame 49, Catasauqua 0 |
| Palisades 54, Northern Lehigh 14 |
| Parkland 24, Stroudsburg 0 |
| Pocono Mountain East 72, East Stroudsburg North 24 |
| Schuylkill Haven 52, Minersville Area 14 |
| Southern Lehigh 54, Pen Argyl 7 |
| Tamaqua Area 49, Lehighton 13 |
| Tri-Valley 33, Newport 8 |
