| 10/13/18 |
| Bermudian Springs 54, York County School of Technology 0 |
| Governor Mifflin 48, Lower Dauphin 7 |
| Middletown Area 42, Trinity 0 |
| 10/12/18 |
| Berks Catholic 41, Schuylkill Valley 7 |
| Bishop McDevitt 38, Hershey 3 |
| Camp Hill 26, Boiling Springs 21 |
| Cedar Cliff 56, Mechanicsburg 7 |
| Central Dauphin East 28, Carlisle 9 |
| Central York 44, Northeastern 7 |
| Cocalico 55, Garden Spot 21 |
| Columbia 26, Octorara Area 21 |
| Conrad Weiser 49, Reading 23 |
| Cumberland Valley 24, Altoona Area 21 |
| Dallastown 63, Spring Grove 24 |
| Daniel Boone 38, Muhlenberg 21 |
| Delone Catholic 57, Fairfield 3 |
| Donegal 35, Annville-Cleona 14 |
| East Pennsboro 21, Steelton-Highspire 20 |
| ELCO 34, Pequea Valley 0 |
| Elizabethtown Area 52, Penn Manor 17 |
| Exeter Township 54, Twin Valley 0 |
| Gettysburg 41, York Suburban 0 |
| Hamburg 24, Fleetwood 21 |
| Harrisburg 28, Chambersburg 13 |
| Hempfield 37, J.P. McCaskey 6 |
| James Buchanan 42, Ceasar Chavez Charter School (DC) 14 |
| Lancaster Catholic 52, Northern Lebanon 7 |
| Lebanon 30, Ephrata 24 |
| Littlestown 45, Biglerville 17 |
| Manheim Central 48, Conestoga Valley 7 |
| Manheim Township 16, Cedar Crest 10 |
| Mifflin County 29, Dover Area 25 |
| Milton Hershey 28, Palmyra 14 |
| Red Lion Area 48, New Oxford 21 |
| Shippensburg Area 7, Northern York 0 |
| Solanco 48, Lampeter-Strasburg 27 |
| State College Area 35, Central Dauphin 28 |
| Susquehanna Township 42, Red Land 7 |
| Susquehannock 43, Eastern York 42 |
| Susquenita 35, Millersburg 6 |
| Upper Dauphin 58, Williams Valley 26 |
| Warwick 38, Wilson West Lawn 12 |
| Waynesboro 43, Greencastle-Antrim 16 |
| West Perry 26, Big Spring 7 |
| West York 32, Kennard-Dale 21 |
| William Penn (3) 49, South Western 21 |
| Wyomissing Area 71, Kutztown 0 |
| York Catholic 55, Hanover 21 |
