| Academy of the New Church 35, Saint Elizabeth (DE) 7 |
| Bangor 50, Pen Argyl 7 |
| Benjamin Franklin 16, Roxborough 14 |
| Berks Catholic 28, Wyomissing Area 7 |
| Bethlehem Liberty 29, Bethlehem Freedom 10 |
| Central Bucks East 24, Pennridge 20 |
| Chester 8, Chichester 6 |
| Conwell-Egan Catholic 39, Cardinal O’Hara 0 |
| Hill School 48, Mercersburg Academy 14 |
| Imani Christian Academy 54, Chartiers-Houston 0 |
| John Bartram 50, Dobbins Randolph Vo-Tech 6 |
| Laurel 60, Northgate 0 |
| Ligonier Valley 45, Shade 8 |
| Louis E. Dieruff 26, William Allen 6 |
| Marion Center 44, Conemaugh Valley 16 |
| Mastery North Charter 32, Jules E. Mastbaum 0 |
| Mohawk Area 34, Summit Academy 20 |
| Neumann-Goretti 53, Lansdale Catholic 34 |
| Notre Dame 56, Wilson Area 24 |
| Pocono Mountain East 22, Pocono Mountain West 0 |
| Purchase Line 50, Ferndale 6 |
| St. Johns Prep (MD) 54, Valley Forge Military Academy 0 |
| Wilkes-Barre Meyers 21, Wilkes-Barre G.A.R. 14 |
