| Academy of the New Church 28, Wilmington Friends (DE) 21 |
| Archbishop Ryan 38, Father Judge 20 |
| Archbishop Wood 42, Roman Catholic 0 |
| Avonworth 35, Summit Academy 8 |
| Beaver Area 49, Ringgold 7 |
| Bethlehem Freedom 55, Pocono Mountain West 6 |
| Bishop McDevitt 26, Neumann-Goretti 0 |
| Cathedral Prep 37, St. Francis (NY) 14 |
| Clarion-Limestone 74, Otto-Eldred 34 |
| Conemaugh Valley 30, Blacklick Valley 27 |
| Conwell-Egan Catholic 42, Archbishop Carroll 27 |
| Ellwood City 27, Western Beaver 21 |
| Governor Mifflin 42, Twin Valley 7 |
| Green Street Academy (Baltimore, MD) 30, Mercersburg Academy 6 |
| Hanover 27, Fairfield 21 |
| Hanover Area 41, Holy Redeemer 12 |
| Hun School (NJ) 33, Haverford School 7 |
| Imani Christian Academy 55, Riverview 0 |
| Imhotep Charter School 36, John Bartram 12 |
| Keystone 52, Sheffield Area 0 |
| Lansdale Catholic 35, Bonner-Prendie 28 |
| Littlestown 62, York County School of Technology 0 |
| Lower Merion 45, Penncrest 7 |
| Loyola Blakefield (MD) 24, Wyoming Seminary 14 |
| Mars Area 21, Shaler Area 12 |
| Morrisville 19, Lower Moreland 18 |
| Nanticoke 47, Crestwood 14 |
| New Hope Solebury 45, Jenkintown 18 |
| Our Lady of the Sacred Heart 55, Laurel 13 |
| Pen Argyl 28, Wilson Area 7 |
| Penn Manor 28, J.P. McCaskey 14 |
| Penn Wood 20, Chester 0 |
| Pennsbury 49, Bensalem 13 |
| Riverside 49, Holy Cross 0 |
| Salisbury Township 35, Catasauqua 7 |
| Sayre 40, Columbia-Montour Vo-Tech 6 |
| Scranton Prep 41, North Pocono 14 |
| Shady Side Academy 63, Apollo-Ridge 21 |
| Souderton Area 21, Central Bucks East 14 |
| Spring-Ford 41, Methacton 7 |
| Springside Chestnut Hill Academy 58, Hill School 27 |
| Union Area 28, Bishop Canevin 0 |
| Valley Forge Military Academy 2, Delaware County Christian School 0 |
| William Penn Charter 45, Blair Academy (NJ) 21 |
| Wyomissing Area 40, Fleetwood 7 |
