District 1
| 10-09 | District 1 | Bristol Warriors (3-1) @. Calvary Christian Academy Cougars (3-1) | 3:30 pm |
| 10-09 | District 1 | Penncrest Lions (3-2) @. Springfield-Delco Cougars (2-3) | 7:00 pm |
| 10-09 | District 1 | Garnet Valley Jaguars (4-1) @. Upper Darby Royals (1-4) | 7:00 pm |
| 10-09 | District 1 | Bensalem Owls (2-3) @. Council Rock North Indians (3-2) | 7:00 pm |
| 10-09 | District 1 | Ridley Green Raiders (5-0) @. Conestoga Pioneers (3-2) | 7:00 pm |
| 10-09 | District 1 | Upper Perkiomen Indians (4-1) @. Owen J. Roberts Wildcats (5-0) | 7:00 pm |
| 10-09 | District 1 | Quakertown Community Panthers (4-1) @. Central Bucks South Titans (1-4) | 7:00 pm |
| 10-09 | District 1 | Lower Merion Aces (1-4) @. Haverford Township Fords (1-4) | 7:00 pm |
| 10-09 | District 1 | St. Pius X Winged Lions (3-2) @. Pottstown Area Trojans (0-5) | 7:00 pm |
| 10-09 | District 1 | Avon Grove Red Devils (4-1) @. West Chester East Vikings (0-5) | 7:00 pm |
| 10-09 | District 1 | Pottsgrove Falcons (5-0) @. Spring-Ford Rams (1-4) | 7:00 pm |
| 10-09 | District 1 | Upper Merion Vikings (3-2) @. Upper Moreland Golden Bears (2-3) | 7:00 pm |
| 10-09 | District 1 | Octorara Area Braves (1-3) @. Caravel Academy (DE) | 7:00 pm |
| 10-09 | District 1 | Boyertown Bears (3-2) @. Perkiomen Valley Vikings (3-2) | 7:00 pm |
| 10-09 | District 1 | Interboro Bucaneers (5-0) @. Academy Park Knights (5-0) | 7:00 pm |
| 10-09 | District 1 | Council Rock South Golden Hawks (4-1) @. Abington Galloping Ghosts (4-0) | 7:00 pm |
| 10-09 | District 1 | Pennridge Rams (2-3) @. Central Bucks East Patriots (0-5) | 7:00 pm |
| 10-09 | District 1 | Chichester Eagles (0-5) @. Glen Mills Battlin Bulls (2-3) | 7:00 pm |
| 10-09 | District 1 | Wissahickon Trojans (3-2) @. Cheltenham Panthers (1-4) | 7:00 pm |
| 10-09 | District 1 | Kennett Blue Demons (1-4) @. Oxford Area Hornets (2-3) | 7:00 pm |
| 10-09 | District 1 | Pennsbury Falcons (5-0) @. Harry S. Truman Tigers (1-4) | 7:00 pm |
| 10-09 | District 1 | Downingtown West Whippets (5-0) @. West Chester Henderson Warriors (5-0) | 7:00 pm |
| 10-09 | District 1 | Strath Haven Panthers (4-1) @. Marple-Newtown Tigers (4-1) | 7:00 pm |
| 10-09 | District 1 | Plymouth-Whitemarsh Colonials (1-4) @. Norristown Eagles (4-1) | 7:00 pm |
| 10-09 | District 1 | Neshaminy Redskins (4-1) @. William Tennent Panthers (1-4) | 7:00 pm |
| 10-09 | District 1 | Harriton Fighting Rams (1-4) @. Radnor Red Raiders (2-3) | 7:30 pm |
| 10-09 | District 1 | Central Bucks West Bucks (1-4) @. North Penn Knights (5-0) | 7:30 pm |
| 10-10 | District 1 | Chester Clippers (1-4) @. Penn Wood Patriots (4-1) | 10:30 am |
| 10-10 | District 1 | Lower Moreland Lions (3-2) @. Springfield-Montco Spartans (1-3) | 1:30 pm |
| 10-10 | District 1 | Methacton Warriors (1-4) @. Phoenixville Phantoms (0-5) | 2:00 pm |
| 10-10 | District 1 | Great Valley Patriots (2-3) @. Unionville Indians (2-3) | 2:00 pm |
| 10-10 | District 1 | Coatesville Red Raiders (2-3) @. Bishop Shanahan Eagles (1-4) | 2:00 pm |
| 10-10 | District 1 | Sun Valley Vanguards (0-5) @. Bayard Rustin Golden Knights (5-0) | 2:30 pm |
| 10-10 | District 1 | New Hope Solebury Lions (0-4) @. Pennington School (NJ) | 2:45 pm |
| 10-10 | District 1 | Hatboro-Horsham Hatters (3-2) @. Souderton Indians (2-3) | 7:00 pm |
District 2
| 10-09 | District 2 | Scranton Knights (4-1) @. Wallenpaupack Buckhorns (3-2) | 7:00 pm |
| 10-09 | District 2 | Dunmore Bucks (5-0) @. Montrose Area Meteors (1-4) | 7:00 pm |
| 10-09 | District 2 | Nanticoke Trojans (1-4) @. Northwest Area Rangers (3-2) | 7:00 pm |
| 10-09 | District 2 | Susquehanna Community Sabers (4-1) @. Mid-Valley Spartans (4-1) | 7:00 pm |
| 10-09 | District 2 | Pittston Area Patriots (2-3) @. Hazleton Area Cougars (3-2) | 7:00 pm |
| 10-09 | District 2 | Old Forge Blue Devils (5-0) @. Holy Cross Crusaders (1-4) | 7:00 pm |
| 10-09 | District 2 | Berwick Area Bulldogs (3-2) @. West Scranton Invaders (1-4) | 7:00 pm |
| 10-09 | District 2 | Lackawanna Trail Lions (0-5) @. Carbondale Area Chargers (2-3) | 7:00 pm |
| 10-09 | District 2 | Wyoming Area Warriors (2-3) @. Wilkes-Barre G.A.R. Grenadiers (3-2) | 7:00 pm |
| 10-09 | District 2 | Honesdale Hornets (0-5) @. Delaware Valley Warriors (2-3) | 7:00 pm |
| 10-09 | District 2 | Abington Heights Comets (5-0) @. North Pocono Trojans (4-1) | 7:00 pm |
| 10-09 | District 2 | Western Wayne Wildcats (3-2) @. Valley View Cougars (1-4) | 7:00 pm |
| 10-09 | District 2 | Wilkes-Barre Meyers Mohawks (2-3) @. Lakeland Chiefs (2-3) | 7:00 pm |
| 10-10 | District 2 | Hanover Area Hawkeyes (3-2) @. Dallas Mountaineers (5-0) | 1:00 pm |
| 10-10 | District 2 | Riverside Vikings (2-3) @. Scranton Prep Cavaliers (4-1) | 1:30 pm |
| 10-10 | District 2 | Lake-Lehman Black Knights (2-3) @. Holy Redeemer Royals (1-4) | 2:00 pm |
| 10-10 | District 2 | Tunkhannock Tigers (0-5) @. Wilkes-Barre Coughlin Crusaders (3-2) | 7:00 pm |
District 3
| 10-09 | District 3 | Fleetwood Tigers (0-5) @. Hamburg Hawks (2-3) | 7:00 pm |
| 10-09 | District 3 | Halifax Wildcats (0-5) @. Williams Valley Vikings (2-3) | 7:00 pm |
| 10-09 | District 3 | Donegal Indians (1-4) @. Annville-Cleona Dutchmen (1-4) | 7:00 pm |
| 10-09 | District 3 | ELCO Raiders (5-0) @. Lampeter-Strasburg Pioneers (2-3) | 7:00 pm |
| 10-09 | District 3 | Wilson West Lawn Bulldogs (4-1) @. Hempfield Black Knights (3-2) | 7:00 pm |
| 10-09 | District 3 | Daniel Boone Blazers (5-0) @. Conrad Weiser Scouts (3-2) | 7:00 pm |
| 10-09 | District 3 | Northeastern Bobcats (3-2) @. West York Bulldogs (5-0) | 7:00 pm |
| 10-09 | District 3 | Dover Area Eagles (0-5) @. Red Lion Area Lions (2-3) | 7:00 pm |
| 10-09 | District 3 | Solanco Golden Mules (2-3) @. Conestoga Valley Buckskins (4-1) | 7:00 pm |
| 10-09 | District 3 | Pequea Valley Braves (1-4) @. Lancaster Catholic Crusaders (4-1) | 7:00 pm |
| 10-09 | District 3 | Warwick Warriors (3-2) @. Reading Knights (2-3) | 7:00 pm |
| 10-09 | District 3 | Shippensburg Area Greyhounds (3-2) @. Mechanicsburg Wildcats (1-4) | 7:00 pm |
| 10-09 | District 3 | Ephrata Mountaineers (0-5) @. Manheim Central Barons (5-0) | 7:00 pm |
| 10-09 | District 3 | Wyomissing Area Spartans (3-2) @. Schuylkill Valley Panthers (3-2) | 7:00 pm |
| 10-09 | District 3 | Manheim Township Blue Streaks (4-1) @. Cedar Crest Falcons (2-3) | 7:00 pm |
| 10-09 | District 3 | Big Spring Bulldogs (2-2) @. Gettysburg Warriors (1-4) | 7:00 pm |
| 10-09 | District 3 | Bermudian Springs Eagles (3-2) @. Susquehannock Warriors (0-5) | 7:00 pm |
| 10-09 | District 3 | Dallastown Wildcats (2-3) @. Central York Panthers (3-2) | 7:00 pm |
| 10-09 | District 3 | New Oxford Colonials (3-2) @. William Penn Bearcats (5-0) | 7:00 pm |
| 10-09 | District 3 | Elizabethtown Area Bears (2-3) @. Garden Spot Spartans (0-5) | 7:00 pm |
| 10-09 | District 3 | Kutztown Cougars (1-4) @. Reading Central Catholic Cardinals (3-2) | 7:00 pm |
| 10-09 | District 3 | J.P. McCaskey Red Tornado (0-5) @. Penn Manor Comets (4-1) | 7:00 pm |
| 10-09 | District 3 | Chambersburg Trojans (3-2) @. Susquehanna Township Indians (5-0) | 7:00 pm |
| 10-09 | District 3 | Cocalico Eagles (4-1) @. Lebanon Cedars (2-3) | 7:00 pm |
| 10-09 | District 3 | Governor Mifflin Mustangs (3-2) @. Blue Mountain Eagles (2-3) | 7:00 pm |
| 10-09 | District 3 | James Buchanan Rockets (0-4) @. Camp Hill Lions (1-3) | 7:00 pm |
| 10-09 | District 3 | Trinity Shamrocks (4-1) @. East Pennsboro Panthers (2-3) | 7:00 pm |
| 10-09 | District 3 | Lower Dauphin Falcons (2-3) @. Cumberland Valley Eagles (4-1) | 7:00 pm |
| 10-09 | District 3 | Twin Valley Raiders (3-2) @. Exeter Township Eagles (1-4) | 7:00 pm |
| 10-09 | District 3 | Carlisle Thundering Herd (2-3) @. Central Dauphin Rams (3-2) | 7:00 pm |
| 10-09 | District 3 | Kennard-Dale Rams (3-2) @. Littlestown Thunderbolts (4-1) | 7:30 pm |
| 10-09 | District 3 | Red Land Patriots (2-3) @. Greencastle-Antrim Blue Devils (5-0) | 7:30 pm |
| 10-09 | District 3 | Hanover Nighthawks (0-4) @. Fairfield Knights (0-5) | 7:30 pm |
| 10-09 | District 3 | York Vo-Tech Spartans (2-3) @. Delone Catholic Squires (4-1) | 7:30 pm |
| 10-09 | District 3 | South Western Mustangs (5-0) @. Spring Grove Rockets (3-2) | 7:30 pm |
| 10-09 | District 3 | Waynesboro Indians (0-5) @. West Perry Mustangs (0-5) | 7:30 pm |
| 10-09 | District 3 | Juniata Indians (3-2) @. Newport Buffaloes (0-5) | 7:30 pm |
| 10-09 | District 3 | York Catholic Fighting Irish (2-3) @. Biglerville Canners (1-4) | 7:30 pm |
| 10-09 | District 3 | York Suburban Trojans (4-1) @. Eastern York Golden Knights (3-2) | 7:30 pm |
| 10-09 | District 3 | Northern Lebanon Vikings (3-2) @. Columbia Crimson Tide (0-5) | 7:30 pm |
| 10-09 | District 3 | Milton Hershey Spartans (2-3) @. Susquenita Blackhawks (3-2) | 7:30 pm |
| 10-09 | District 3 | Hershey Trojans (4-1) @. Northern Polar Bears (5-0) | 7:30 pm |
| 10-10 | District 3 | Holy Name Blue Jays (3-2) @. Pius X Royals (2-2) | 1:00 pm |
| 10-10 | District 3 | Central Dauphin East Panthers (0-5) @. Harrisburg Cougars (1-4) | 1:00 pm |
| 10-10 | District 3 | Steelton-Highspire Steamrollers (3-1) @. Middletown Area Blue Raiders (4-1) | 2:00 pm |
| 10-10 | District 3 | Carson Long Institute Military Warriors (0-4) @. Columbia-Montour Vo-Tech Rams (2-3) | 2:00 pm |
| 10-10 | District 3 | Palmyra Cougars (4-1) @. Red Lion Christian Academy (DE) | 7:00 pm |
| 10-10 | District 3 | Millersburg Indians (2-3) @. East Juniata Tigers (4-1) | 7:00 pm |
District 4
| 10-09 | District 4 | Williamsport Millionaires (4-1) @. Crestwood Comets (3-2) | 7:00 pm |
| 10-09 | District 4 | Canton Area Warriors (2-3) @. Montgomery Red Raiders (2-3) | 7:00 pm |
| 10-09 | District 4 | Athens Wildcats (3-2) @. Troy Area Trojans (4-1) | 7:00 pm |
| 10-09 | District 4 | Shikellamy Braves (4-1) @. Montoursville Warriors (5-0) | 7:00 pm |
| 10-09 | District 4 | Southern Columbia Tigers (3-2) @. Bloomsburg Panthers (3-2) | 7:00 pm |
| 10-09 | District 4 | Warrior Run Defenders (0-5) @. Muncy Indians (2-3) | 7:00 pm |
| 10-09 | District 4 | Milton Area Black Panthers (1-4) @. Boiling Springs Bubblers (1-4) | 7:00 pm |
| 10-09 | District 4 | Loyalsock Township Lancers (4-1) @. Mount Carmel Area Red Tornadoes (3-2) | 7:00 pm |
| 10-09 | District 4 | Lewisburg Green Dragons (4-1) @. Central Columbia Blue Jays (1-4) | 7:00 pm |
| 10-09 | District 4 | Jersey Shore Bulldogs (0-5) @. Mifflinburg Wildcats (2-3) | 7:00 pm |
| 10-09 | District 4 | Our Lady of Lourdes Red Raiders (2-2) @. Bucktail Bucks (1-3) | 7:00 pm |
| 10-09 | District 4 | Danville Ironmen (3-2) @. Hughesville Spartans (5-0) | 7:00 pm |
| 10-09 | District 4 | Line Mountain Eagles (5-0) @. Tri-Valley Bulldogs (3-2) | 7:00 pm |
| 10-09 | District 4 | Shamokin Indians (1-4) @. Selinsgrove Seals (5-0) | 7:00 pm |
| 10-09 | District 4 | Towanda Black Knights (5-0) @. Wellsboro Hornets (1-4) | 7:00 pm |
| 10-09 | District 4 | North Penn Panthers (2-3) @. Wyalusing Valley Rams (3-2) | 7:00 pm |
| 10-10 | District 4 | South Williamsport Mounties (0-5) @. Sayre Redskins (2-3) | 7:00 pm |
District 11
| 10-09 | District 11 | Lehighton Indians (1-4) @. East Stroudsburg South Cavaliers (4-1) | 7:00 pm |
| 10-09 | District 11 | Panther Valley Panthers (4-1) @. Marian Catholic Colts (1-4) | 7:00 pm |
| 10-09 | District 11 | Pocono Mountain East Cardinals (2-3) @. East Stroudsburg North Timberwolves (3-2) | 7:00 pm |
| 10-09 | District 11 | Palmerton Area Blue Bombers (1-4) @. Northwestern Lehigh Tigers (3-2) | 7:00 pm |
| 10-09 | District 11 | Bethlehem Catholic Golden Hawks (3-2) @. Bethlehem Liberty Hurricanes (2-3) | 7:00 pm |
| 10-09 | District 11 | Minersville Area Battlin’ Miners (1-4) @. Jim Thorpe Area Olympians (1-4) | 7:00 pm |
| 10-09 | District 11 | Pleasant Valley Bears (2-3) @. Pocono Mountain West Panthers (0-5) | 7:00 pm |
| 10-09 | District 11 | Notre Dame Crusaders (0-5) @. Southern Lehigh Spartans (4-1) | 7:00 pm |
| 10-09 | District 11 | Nazareth Area Blue Eagles (3-2) @. Easton Area Red Rovers (4-1) | 7:00 pm |
| 10-09 | District 11 | Pottsville Area Crimson Tide (3-2) @. Muhlenberg Muhls (4-1) | 7:00 pm |
| 10-09 | District 11 | Bethlehem Freedom Patriots (4-1) @. Northampton Koncrete Kids (3-2) | 7:00 pm |
| 10-09 | District 11 | Catasauqua Rough Riders (4-1) @. Bangor Slaters (1-4) | 7:00 pm |
| 10-09 | District 11 | Pine Grove Area Cardinals (2-3) @. Upper Dauphin Trojans (5-0) | 7:00 pm |
| 10-09 | District 11 | William Allen Canaries (0-5) @. Parkland Trojans (3-2) | 7:00 pm |
| 10-09 | District 11 | North Schuylkill Spartans (5-0) @. Tamaqua Area Blue Raiders (5-0) | 7:00 pm |
| 10-09 | District 11 | Wilson Area Warriors (5-0) @. Palisades Pirates (3-2) | 7:00 pm |
| 10-09 | District 11 | Emmaus Hornets (3-2) @. Louis E. Dieruff Huskies (0-5) | 7:00 pm |
| 10-09 | District 11 | Shenandoah Valley Blue Devils (3-2) @. Schuylkill Haven Hurricanes (3-2) | 7:00 pm |
| 10-09 | District 11 | Stroudsburg Mounties (1-4) @. Wyoming Valley West Spartans (3-2) | 7:00 pm |
| 10-09 | District 11 | Saucon Valley Panthers (2-3) @. Salisbury Township Falcons (1-4) | 7:00 pm |
| 10-10 | District 11 | Mahanoy Area Golden Bears (0-5) @. Jenkintown Drakes (1-4) | 1:00 pm |
| 10-10 | District 11 | Northern Lehigh Bulldogs (4-1) @. Pen Argyl Green Knights (2-3) | 1:30 pm |
| 10-10 | District 11 | Nativity BVM Green Wave (2-3) @. Delaware Military | 2:00 pm |
| 10-10 | District 11 | Whitehall Zephyrs (2-3) @. Allentown Central Catholic Vikings (5-0) | 7:00 pm |
District 12
| 10-08 | District 12 | Edward Bok Vo-Tech Wildcats (5-0) @. FitzSimons Thomas Rams (0-5) | 3:00 pm |
| 10-08 | District 12 | John Bartram Maroon Wave (4-1) @. Jules E. Mastbaum Panthers (1-3) | 3:00 pm |
| 10-08 | District 12 | Olney Trojans (3-0) @. Abraham Lincoln Rail Splitters (2-3) | 6:00 pm |
| 10-08 | District 12 | Benjamin Franklin Electrons (3-2) @. Furness Falcons (3-2) | 6:00 pm |
| 10-09 | District 12 | Philadelphia Central Lancers (3-1) @. Thomas Edison Owls (0-5) | 3:00 pm |
| 10-09 | District 12 | West Philadelphia Speedboys (2-3) @. Samuel S. Fels Panthers (1-4) | 3:00 pm |
| 10-09 | District 12 | South Philadelphia Rams (1-3) @. Martin Luther King Golden Cougars (2-3) | 3:00 pm |
| 10-09 | District 12 | Simon Gratz Bulldogs (3-2) @. Dobbins Randolph Vo-Tech Mustangs (3-2) | 3:00 pm |
| 10-09 | District 12 | Communications Technology Phoenix (1-4) @. Prep Charter Huskies (2-3) | 6:00 pm |
| 10-09 | District 12 | Overbrook Panthers (1-4) @. Northeast Vikings (3-2) | 6:00 pm |
| 10-09 | District 12 | Roxborough Indians (2-3) @. William Penn Lions (3-1) | 6:00 pm |
| 10-09 | District 12 | Conwell Egan Catholic Eagles (3-2) @. Lansdale Catholic Crusaders (0-5) | 7:00 pm |
| 10-09 | District 12 | Father Judge Crusaders (4-1) @. LaSalle Explorers (4-1) | 7:00 pm |
| 10-09 | District 12 | University City Jaguars (0-4) @. Germantown Bears (1-3) | 7:00 pm |
| 10-09 | District 12 | Kennedy-Kenrick Catholic Wolverines (1-4) @. West Catholic Burrs (3-2) | 7:30 pm |
| 10-10 | District 12 | Archbishop Carroll Patriots (1-4) @. Northeast Catholic Falcons (2-3) | 1:00 pm |
| 10-10 | District 12 | Archbishop Ryan Raiders (0-5) @. Saint Joseph’s Prep Hawks (4-1) | 1:00 pm |
| 10-10 | District 12 | Monsignor Bonner Friars (2-3) @. Chestnut Hill Academy Blue Devils (4-0) | 2:30 pm |
| 10-10 | District 12 | School of the Future (3-2) @. Delaware Valley Charter Warriors (3-2) | 3:00 pm |
| 10-10 | District 12 | George Washington Eagles (3-2) @. Frankford Pioneers (1-4) | 6:00 pm |
| 10-10 | District 12 | Nueva Esperenza Charter Toros (0-4) @. Imhotep Charter School Panthers (3-1) | 6:00 pm |
| 10-10 | District 12 | Cardinal Dougherty Cardinals (3-1) @. Bishop McDevitt Lancers (5-0) | 7:00 pm |
| 10-10 | District 12 | Neumann-Goretti Saints (1-4) @. Archbishop Wood Vikings (3-2) | 7:00 pm |
| 10-11 | District 12 | Roman Catholic Cahillites (2-3) @. Cardinal O’Hara Lions (5-0) | 1:00 pm |
Non-PIAA Teams
| 10-09 | Non-Pennsylvania | Peddie School (NJ) @. Hill School Blues (2-1) | 3:30 pm |
| 10-09 | Non-Pennsylvania | Freedom Village (NY) @. Cowanesque Valley Indians (0-5) | 7:00 pm |
| 10-10 | Non-Pennsylvania | Tower Hill School (DE) @. George School Cougars (1-2) | 1:00 pm |
| 10-10 | Non-Pennsylvania | East Coast Knights @. Wyoming Seminary Blue Knights (3-1) | 2:00 pm |
| 10-10 | Non-Pennsylvania | Dwight-Englewood @. Morrisville Bulldogs (4-1) | 7:00 pm |
